The use of transparent inks in combination with underbasing and halftoning can create an incredible variety of textures, finishes and visual colors. By having certain areas overlaying on paper color only, while other colors lay over a white underbase, it maximizes the use of 3 colors to create a wide variety of colors.
This kind of design forethought can be achieved with a deep knowledge of the screen printing process and its intended results. Without knowing how colors will shift on papers and how to use halftones to create those multiple layers, one would have a very hard time designing something like this. Taking the screen print process into consideration while creating your design can yield much better results.